Chemistry of Spontaneous Alkylation of Methimazole with 1,2-Dichloroethane

Spontaneous S-alkylation of methimazole (1) with 1,2-dichloroethane (DCE) into 1,2-bis[(1-methyl-1H-imidazole-2-yl)thio]ethane (2), that we have described recently, opened the question about its formation pathway(s). Results of the synthetic, NMR spectroscopic, crystallographic and computational stu...

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Detalles Bibliográficos
Autores principales: Štefan, Leo, Čikoš, Ana, Vianello, Robert, Đilović, Ivica, Matković-Čalogović, Dubravka, Dumić, Miljenko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625577/
https://www.ncbi.nlm.nih.gov/pubmed/34834123
http://dx.doi.org/10.3390/molecules26227032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625577/
https://www.ncbi.nlm.nih.gov/pubmed/34834123
http://dx.doi.org/10.3390/molecules26227032

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