Efficient Control of Zika Virus Infection Induced by a Non-Replicating Adenovector Encoding Zika Virus NS1/NS2 Antigens Fused to the MHC Class II-Associated Invariant Chain

It is generally believed that a successful Zika virus (ZIKV) vaccine should induce neutralizing antibodies against the ZIKV envelope (E) protein to efficiently halt viral infection. However, E-specific neutralizing antibodies have been implicated in a phenomenon called antibody-dependent enhancement...

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Detalles Bibliográficos
Autores principales: Nazerai, Loulieta, Buus, Søren, Stryhn, Anette, Thomsen, Allan Randrup, Christensen, Jan Pravsgaard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625593/
https://www.ncbi.nlm.nih.gov/pubmed/34835021
http://dx.doi.org/10.3390/v13112215

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