Synthesis and Structure-Activity Relationships of New 2-Phenoxybenzamides with Antiplasmodial Activity

The 2-phenoxybenzamide 1 from the Medicines for Malaria Venture Malaria Box Project has shown promising multi-stage activity against different strains of P. falciparum. It was successfully synthesized via a retrosynthetic approach. Subsequently, twenty-one new derivatives were prepared and tested fo...

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Detalles Bibliográficos
Autores principales: Hermann, Theresa, Hochegger, Patrick, Dolensky, Johanna, Seebacher, Werner, Pferschy-Wenzig, Eva-Maria, Saf, Robert, Kaiser, Marcel, Mäser, Pascal, Weis, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625693/
https://www.ncbi.nlm.nih.gov/pubmed/34832891
http://dx.doi.org/10.3390/ph14111109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625693/
https://www.ncbi.nlm.nih.gov/pubmed/34832891
http://dx.doi.org/10.3390/ph14111109

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