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MRI Findings in Hip in Juvenile Idiopathic Arthritis

The aim of this study was to evaluate if magnetic resonance imaging allows hip arthritis in JIA to be differentiated from hip arthralgia of unknown etiology in juveniles clinically suspected for hip arthritis. This was a retrospective observational study which included 97 children with clinically su...

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Autores principales: Ostrowska, Monika, Gietka, Piotr, Mańczak, Małgorzata, Michalski, Emil, Sudoł-Szopińska, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625848/
https://www.ncbi.nlm.nih.gov/pubmed/34830537
http://dx.doi.org/10.3390/jcm10225252
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author Ostrowska, Monika
Gietka, Piotr
Mańczak, Małgorzata
Michalski, Emil
Sudoł-Szopińska, Iwona
author_facet Ostrowska, Monika
Gietka, Piotr
Mańczak, Małgorzata
Michalski, Emil
Sudoł-Szopińska, Iwona
author_sort Ostrowska, Monika
collection PubMed
description The aim of this study was to evaluate if magnetic resonance imaging allows hip arthritis in JIA to be differentiated from hip arthralgia of unknown etiology in juveniles clinically suspected for hip arthritis. This was a retrospective observational study which included 97 children with clinically suspected hip arthritis. Each hip was assessed and scored in MRI for signs of active and destructive inflammatory lesions and developmental lesions. MRI findings between JIA-confirmed patients and without final diagnosis of JIA were compared and the MRI summarized score was calculated, as the sum of scorings of all 24 hip lesions in an individual patient (i.a., effusion, synovitis, bone marrow edema, enthesitis). MRI showed at least one lesion in the majority of patients (95 patients; 98%). Effusion was the most common feature, followed by bone marrow oedema and synovitis. All lesions were more common in patients with a final diagnosis of JIA, especially synovitis and enthesitis (p = 0.037 and p = 0.047). The MRI summarized score was significantly higher in the JIA group than the non-JIA group: 3 (2–5) vs. 2 (2–2), respectively, p = 0.002. Using a cut-off score of 6, the MRI summarized score showed 25% sensitivity and 100% specificity indicating a good ability in discriminating hip arthritis during JIA from non-JIA patients. MRI allows hip arthritis in JIA to be differentiated from hip arthralgia of unknown etiology with good specificity, thus, may be helpful in confirming the diagnosis of JIA.
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spelling pubmed-86258482021-11-27 MRI Findings in Hip in Juvenile Idiopathic Arthritis Ostrowska, Monika Gietka, Piotr Mańczak, Małgorzata Michalski, Emil Sudoł-Szopińska, Iwona J Clin Med Article The aim of this study was to evaluate if magnetic resonance imaging allows hip arthritis in JIA to be differentiated from hip arthralgia of unknown etiology in juveniles clinically suspected for hip arthritis. This was a retrospective observational study which included 97 children with clinically suspected hip arthritis. Each hip was assessed and scored in MRI for signs of active and destructive inflammatory lesions and developmental lesions. MRI findings between JIA-confirmed patients and without final diagnosis of JIA were compared and the MRI summarized score was calculated, as the sum of scorings of all 24 hip lesions in an individual patient (i.a., effusion, synovitis, bone marrow edema, enthesitis). MRI showed at least one lesion in the majority of patients (95 patients; 98%). Effusion was the most common feature, followed by bone marrow oedema and synovitis. All lesions were more common in patients with a final diagnosis of JIA, especially synovitis and enthesitis (p = 0.037 and p = 0.047). The MRI summarized score was significantly higher in the JIA group than the non-JIA group: 3 (2–5) vs. 2 (2–2), respectively, p = 0.002. Using a cut-off score of 6, the MRI summarized score showed 25% sensitivity and 100% specificity indicating a good ability in discriminating hip arthritis during JIA from non-JIA patients. MRI allows hip arthritis in JIA to be differentiated from hip arthralgia of unknown etiology with good specificity, thus, may be helpful in confirming the diagnosis of JIA. MDPI 2021-11-11 /pmc/articles/PMC8625848/ /pubmed/34830537 http://dx.doi.org/10.3390/jcm10225252 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ostrowska, Monika
Gietka, Piotr
Mańczak, Małgorzata
Michalski, Emil
Sudoł-Szopińska, Iwona
MRI Findings in Hip in Juvenile Idiopathic Arthritis
title MRI Findings in Hip in Juvenile Idiopathic Arthritis
title_full MRI Findings in Hip in Juvenile Idiopathic Arthritis
title_fullStr MRI Findings in Hip in Juvenile Idiopathic Arthritis
title_full_unstemmed MRI Findings in Hip in Juvenile Idiopathic Arthritis
title_short MRI Findings in Hip in Juvenile Idiopathic Arthritis
title_sort mri findings in hip in juvenile idiopathic arthritis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625848/
https://www.ncbi.nlm.nih.gov/pubmed/34830537
http://dx.doi.org/10.3390/jcm10225252
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