Genomic Instability and Cancer Risk Associated with Erroneous DNA Repair

Many cancers develop as a consequence of genomic instability, which induces genomic rearrangements and nucleotide mutations. Failure to correct DNA damage in DNA repair defective cells, such as in BRCA1 and BRCA2 mutated backgrounds, is directly associated with increased cancer risk. Genomic rearran...

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Detalles Bibliográficos
Autores principales: Yoshioka, Ken-ichi, Kusumoto-Matsuo, Rika, Matsuno, Yusuke, Ishiai, Masamichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625880/
https://www.ncbi.nlm.nih.gov/pubmed/34830134
http://dx.doi.org/10.3390/ijms222212254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625880/
https://www.ncbi.nlm.nih.gov/pubmed/34830134
http://dx.doi.org/10.3390/ijms222212254

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