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Arginase 2 and Polyamines in Human Pancreatic Beta Cells: Possible Role in the Pathogenesis of Type 2 Diabetes

Arginase 2 (ARG2) is a manganese metalloenzyme involved in several tissue specific processes, from physiology to pathophysiology. It is variably expressed in extra-hepatic tissues and is located in the mitochondria. In human pancreatic beta cells, ARG2 is downregulated in type 2 diabetes. The enzyme...

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Detalles Bibliográficos
Autores principales: Marselli, Lorella, Bosi, Emanuele, De Luca, Carmela, Del Guerra, Silvia, Tesi, Marta, Suleiman, Mara, Marchetti, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625980/
https://www.ncbi.nlm.nih.gov/pubmed/34829980
http://dx.doi.org/10.3390/ijms222212099