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Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital

SARS-CoV-2 transmission has been high, especially among healthcare workers worldwide during the first wave. Vaccination is recognized as the most effective approach to combat the pandemic, but hesitation to get vaccinated represents an obstacle. Another important issue is the duration of protection...

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Autores principales: Forgeschi, Guglielmo, Cavallo, Giuseppe, Lorini, Chiara, Balboni, Fiamma, Sequi, Francesca, Bonaccorsi, Guglielmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625988/
https://www.ncbi.nlm.nih.gov/pubmed/34835263
http://dx.doi.org/10.3390/vaccines9111332
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author Forgeschi, Guglielmo
Cavallo, Giuseppe
Lorini, Chiara
Balboni, Fiamma
Sequi, Francesca
Bonaccorsi, Guglielmo
author_facet Forgeschi, Guglielmo
Cavallo, Giuseppe
Lorini, Chiara
Balboni, Fiamma
Sequi, Francesca
Bonaccorsi, Guglielmo
author_sort Forgeschi, Guglielmo
collection PubMed
description SARS-CoV-2 transmission has been high, especially among healthcare workers worldwide during the first wave. Vaccination is recognized as the most effective approach to combat the pandemic, but hesitation to get vaccinated represents an obstacle. Another important issue is the duration of protection after administration of the full vaccination cycle. Based on these premises, we conducted a study to evaluate vaccination adherence and the anti-S antibodies levels among hospital workers, from January to March, 2021. To assess adherence, an anonymous questionnaire was used. Anti-S antibody levels were obtained from the monitoring serological sample database. In total, 56.2% of the unvaccinated people did not report a previous infection from COVID-19. Among those who have not been vaccinated, 12.5% showed distrust against the vaccine, 8.3% stated to have received contraindications to the vaccination, and 6.3% did not report any choice. Analyzing anti-S antibody levels, only one person was found to have a value below the lower cut-off, two weeks, and three months after receiving their second dose. One was below the cut-off after two weeks, and then above the same cut-off after three months. The results of our survey should be seen as a stimulus to further sensitize hospital staff to the importance of vaccination and pay attention to anti-S antibody levels monitoring.
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spelling pubmed-86259882021-11-27 Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital Forgeschi, Guglielmo Cavallo, Giuseppe Lorini, Chiara Balboni, Fiamma Sequi, Francesca Bonaccorsi, Guglielmo Vaccines (Basel) Brief Report SARS-CoV-2 transmission has been high, especially among healthcare workers worldwide during the first wave. Vaccination is recognized as the most effective approach to combat the pandemic, but hesitation to get vaccinated represents an obstacle. Another important issue is the duration of protection after administration of the full vaccination cycle. Based on these premises, we conducted a study to evaluate vaccination adherence and the anti-S antibodies levels among hospital workers, from January to March, 2021. To assess adherence, an anonymous questionnaire was used. Anti-S antibody levels were obtained from the monitoring serological sample database. In total, 56.2% of the unvaccinated people did not report a previous infection from COVID-19. Among those who have not been vaccinated, 12.5% showed distrust against the vaccine, 8.3% stated to have received contraindications to the vaccination, and 6.3% did not report any choice. Analyzing anti-S antibody levels, only one person was found to have a value below the lower cut-off, two weeks, and three months after receiving their second dose. One was below the cut-off after two weeks, and then above the same cut-off after three months. The results of our survey should be seen as a stimulus to further sensitize hospital staff to the importance of vaccination and pay attention to anti-S antibody levels monitoring. MDPI 2021-11-16 /pmc/articles/PMC8625988/ /pubmed/34835263 http://dx.doi.org/10.3390/vaccines9111332 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Forgeschi, Guglielmo
Cavallo, Giuseppe
Lorini, Chiara
Balboni, Fiamma
Sequi, Francesca
Bonaccorsi, Guglielmo
Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital
title Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital
title_full Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital
title_fullStr Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital
title_full_unstemmed Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital
title_short Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital
title_sort investigating adherence to covid-19 vaccination and serum antibody concentration among hospital workers—the experience of an italian private hospital
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625988/
https://www.ncbi.nlm.nih.gov/pubmed/34835263
http://dx.doi.org/10.3390/vaccines9111332
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