Cargando…
Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital
SARS-CoV-2 transmission has been high, especially among healthcare workers worldwide during the first wave. Vaccination is recognized as the most effective approach to combat the pandemic, but hesitation to get vaccinated represents an obstacle. Another important issue is the duration of protection...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625988/ https://www.ncbi.nlm.nih.gov/pubmed/34835263 http://dx.doi.org/10.3390/vaccines9111332 |
_version_ | 1784606556502884352 |
---|---|
author | Forgeschi, Guglielmo Cavallo, Giuseppe Lorini, Chiara Balboni, Fiamma Sequi, Francesca Bonaccorsi, Guglielmo |
author_facet | Forgeschi, Guglielmo Cavallo, Giuseppe Lorini, Chiara Balboni, Fiamma Sequi, Francesca Bonaccorsi, Guglielmo |
author_sort | Forgeschi, Guglielmo |
collection | PubMed |
description | SARS-CoV-2 transmission has been high, especially among healthcare workers worldwide during the first wave. Vaccination is recognized as the most effective approach to combat the pandemic, but hesitation to get vaccinated represents an obstacle. Another important issue is the duration of protection after administration of the full vaccination cycle. Based on these premises, we conducted a study to evaluate vaccination adherence and the anti-S antibodies levels among hospital workers, from January to March, 2021. To assess adherence, an anonymous questionnaire was used. Anti-S antibody levels were obtained from the monitoring serological sample database. In total, 56.2% of the unvaccinated people did not report a previous infection from COVID-19. Among those who have not been vaccinated, 12.5% showed distrust against the vaccine, 8.3% stated to have received contraindications to the vaccination, and 6.3% did not report any choice. Analyzing anti-S antibody levels, only one person was found to have a value below the lower cut-off, two weeks, and three months after receiving their second dose. One was below the cut-off after two weeks, and then above the same cut-off after three months. The results of our survey should be seen as a stimulus to further sensitize hospital staff to the importance of vaccination and pay attention to anti-S antibody levels monitoring. |
format | Online Article Text |
id | pubmed-8625988 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86259882021-11-27 Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital Forgeschi, Guglielmo Cavallo, Giuseppe Lorini, Chiara Balboni, Fiamma Sequi, Francesca Bonaccorsi, Guglielmo Vaccines (Basel) Brief Report SARS-CoV-2 transmission has been high, especially among healthcare workers worldwide during the first wave. Vaccination is recognized as the most effective approach to combat the pandemic, but hesitation to get vaccinated represents an obstacle. Another important issue is the duration of protection after administration of the full vaccination cycle. Based on these premises, we conducted a study to evaluate vaccination adherence and the anti-S antibodies levels among hospital workers, from January to March, 2021. To assess adherence, an anonymous questionnaire was used. Anti-S antibody levels were obtained from the monitoring serological sample database. In total, 56.2% of the unvaccinated people did not report a previous infection from COVID-19. Among those who have not been vaccinated, 12.5% showed distrust against the vaccine, 8.3% stated to have received contraindications to the vaccination, and 6.3% did not report any choice. Analyzing anti-S antibody levels, only one person was found to have a value below the lower cut-off, two weeks, and three months after receiving their second dose. One was below the cut-off after two weeks, and then above the same cut-off after three months. The results of our survey should be seen as a stimulus to further sensitize hospital staff to the importance of vaccination and pay attention to anti-S antibody levels monitoring. MDPI 2021-11-16 /pmc/articles/PMC8625988/ /pubmed/34835263 http://dx.doi.org/10.3390/vaccines9111332 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Brief Report Forgeschi, Guglielmo Cavallo, Giuseppe Lorini, Chiara Balboni, Fiamma Sequi, Francesca Bonaccorsi, Guglielmo Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital |
title | Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital |
title_full | Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital |
title_fullStr | Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital |
title_full_unstemmed | Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital |
title_short | Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private Hospital |
title_sort | investigating adherence to covid-19 vaccination and serum antibody concentration among hospital workers—the experience of an italian private hospital |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625988/ https://www.ncbi.nlm.nih.gov/pubmed/34835263 http://dx.doi.org/10.3390/vaccines9111332 |
work_keys_str_mv | AT forgeschiguglielmo investigatingadherencetocovid19vaccinationandserumantibodyconcentrationamonghospitalworkerstheexperienceofanitalianprivatehospital AT cavallogiuseppe investigatingadherencetocovid19vaccinationandserumantibodyconcentrationamonghospitalworkerstheexperienceofanitalianprivatehospital AT lorinichiara investigatingadherencetocovid19vaccinationandserumantibodyconcentrationamonghospitalworkerstheexperienceofanitalianprivatehospital AT balbonifiamma investigatingadherencetocovid19vaccinationandserumantibodyconcentrationamonghospitalworkerstheexperienceofanitalianprivatehospital AT sequifrancesca investigatingadherencetocovid19vaccinationandserumantibodyconcentrationamonghospitalworkerstheexperienceofanitalianprivatehospital AT bonaccorsiguglielmo investigatingadherencetocovid19vaccinationandserumantibodyconcentrationamonghospitalworkerstheexperienceofanitalianprivatehospital |