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Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts
The post-translational modification of histones by the small ubiquitin-like modifier (SUMO) protein has been associated with gene regulation, centromeric localization, and double-strand break repair in eukaryotes. Although sumoylation of histone H4 was specifically associated with gene repression, t...
Autores principales: | Leonen, Calvin Jon A, Shimada, Miho, Weller, Caroline E, Nakadai, Tomoyoshi, Hsu, Peter L, Tyson, Elizabeth L, Mishra, Arpit, Shelton, Patrick MM, Sadilek, Martin, Hawkins, R David, Zheng, Ning, Roeder, Robert G, Chatterjee, Champak |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626089/ https://www.ncbi.nlm.nih.gov/pubmed/34747692 http://dx.doi.org/10.7554/eLife.67952 |
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