Differences in the case fatality risks associated with SARS-CoV-2 Delta and non-Delta variants in relation to vaccine coverage: An early ecological study in the United Kingdom

The circulation of SARS-CoV-2 Delta (i.e., B.1.617.2) variants challenges the pandemic control. Our analysis showed that in the United Kingdom (UK), the reported case fatality ratio (CFR) decreased from May to July 2021 for non-Delta variant, whereas the decreasing trends of the CFR of Delta variant...

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Detalles Bibliográficos
Autores principales: Zhao, Shi, Lou, Jingzhi, Cao, Lirong, Chong, Ka Chun, Zee, Benny C.Y., Chan, Paul K.S., Wang, Maggie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626151/
https://www.ncbi.nlm.nih.gov/pubmed/34843993
http://dx.doi.org/10.1016/j.meegid.2021.105162
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author Zhao, Shi
Lou, Jingzhi
Cao, Lirong
Chong, Ka Chun
Zee, Benny C.Y.
Chan, Paul K.S.
Wang, Maggie H.
author_facet Zhao, Shi
Lou, Jingzhi
Cao, Lirong
Chong, Ka Chun
Zee, Benny C.Y.
Chan, Paul K.S.
Wang, Maggie H.
author_sort Zhao, Shi
collection PubMed
description The circulation of SARS-CoV-2 Delta (i.e., B.1.617.2) variants challenges the pandemic control. Our analysis showed that in the United Kingdom (UK), the reported case fatality ratio (CFR) decreased from May to July 2021 for non-Delta variant, whereas the decreasing trends of the CFR of Delta variant appeared weak and insignificant. The association between vaccine coverage and CFR might be stratified by different circulating variants. Due to the limitation of ecological study design, the interpretation of our results should be treated with caution.
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spelling pubmed-86261512021-11-29 Differences in the case fatality risks associated with SARS-CoV-2 Delta and non-Delta variants in relation to vaccine coverage: An early ecological study in the United Kingdom Zhao, Shi Lou, Jingzhi Cao, Lirong Chong, Ka Chun Zee, Benny C.Y. Chan, Paul K.S. Wang, Maggie H. Infect Genet Evol Short Communication The circulation of SARS-CoV-2 Delta (i.e., B.1.617.2) variants challenges the pandemic control. Our analysis showed that in the United Kingdom (UK), the reported case fatality ratio (CFR) decreased from May to July 2021 for non-Delta variant, whereas the decreasing trends of the CFR of Delta variant appeared weak and insignificant. The association between vaccine coverage and CFR might be stratified by different circulating variants. Due to the limitation of ecological study design, the interpretation of our results should be treated with caution. The Authors. Published by Elsevier B.V. 2022-01 2021-11-27 /pmc/articles/PMC8626151/ /pubmed/34843993 http://dx.doi.org/10.1016/j.meegid.2021.105162 Text en © 2021 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Communication
Zhao, Shi
Lou, Jingzhi
Cao, Lirong
Chong, Ka Chun
Zee, Benny C.Y.
Chan, Paul K.S.
Wang, Maggie H.
Differences in the case fatality risks associated with SARS-CoV-2 Delta and non-Delta variants in relation to vaccine coverage: An early ecological study in the United Kingdom
title Differences in the case fatality risks associated with SARS-CoV-2 Delta and non-Delta variants in relation to vaccine coverage: An early ecological study in the United Kingdom
title_full Differences in the case fatality risks associated with SARS-CoV-2 Delta and non-Delta variants in relation to vaccine coverage: An early ecological study in the United Kingdom
title_fullStr Differences in the case fatality risks associated with SARS-CoV-2 Delta and non-Delta variants in relation to vaccine coverage: An early ecological study in the United Kingdom
title_full_unstemmed Differences in the case fatality risks associated with SARS-CoV-2 Delta and non-Delta variants in relation to vaccine coverage: An early ecological study in the United Kingdom
title_short Differences in the case fatality risks associated with SARS-CoV-2 Delta and non-Delta variants in relation to vaccine coverage: An early ecological study in the United Kingdom
title_sort differences in the case fatality risks associated with sars-cov-2 delta and non-delta variants in relation to vaccine coverage: an early ecological study in the united kingdom
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626151/
https://www.ncbi.nlm.nih.gov/pubmed/34843993
http://dx.doi.org/10.1016/j.meegid.2021.105162
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