Cargando…

The B-type natriuretic peptide of the Congo and Timneh grey parrot

In captivity, cardiovascular diseases are common in grey parrots. The diagnosis of these diseases in living birds is difficult, and new diagnostic possibilities would be desirable. The heart is an important endocrine organ in which cardiomyocytes synthetise B-type natriuretic peptide (BNP) and relea...

Descripción completa

Detalles Bibliográficos
Autores principales: Hennig, Anja, Mohr, L., Fehr, M., Legler, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626375/
https://www.ncbi.nlm.nih.gov/pubmed/34278549
http://dx.doi.org/10.1007/s11259-021-09813-3
_version_ 1784606643056541696
author Hennig, Anja
Mohr, L.
Fehr, M.
Legler, M.
author_facet Hennig, Anja
Mohr, L.
Fehr, M.
Legler, M.
author_sort Hennig, Anja
collection PubMed
description In captivity, cardiovascular diseases are common in grey parrots. The diagnosis of these diseases in living birds is difficult, and new diagnostic possibilities would be desirable. The heart is an important endocrine organ in which cardiomyocytes synthetise B-type natriuretic peptide (BNP) and release it into the bloodstream. This hormone has a significant role in cardiovascular and body fluid regulation. The blood concentration of BNP is used in human medicine and small animal medicine as a diagnostic tool in the identification of heart diseases and as a prognostic marker for the risk of mortality. The nucleotide and amino acid sequence of BNP was described in Congo (n = 4) and Timneh (n = 3) grey parrots by PCR after RNA isolation from the atria and ventricles. The results showed a high similarity between the nucleotide sequences of the grey parrots’ BNP and the already known sequence of this hormone in chickens. The amino acid sequence of the mature peptide region is consistent in these three species. BNP plasma concentration could be a possible blood parameter for identifying clinically manifest cardiovascular diseases in grey parrots as it is in other species.
format Online
Article
Text
id pubmed-8626375
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Springer Netherlands
record_format MEDLINE/PubMed
spelling pubmed-86263752021-12-01 The B-type natriuretic peptide of the Congo and Timneh grey parrot Hennig, Anja Mohr, L. Fehr, M. Legler, M. Vet Res Commun Original Article In captivity, cardiovascular diseases are common in grey parrots. The diagnosis of these diseases in living birds is difficult, and new diagnostic possibilities would be desirable. The heart is an important endocrine organ in which cardiomyocytes synthetise B-type natriuretic peptide (BNP) and release it into the bloodstream. This hormone has a significant role in cardiovascular and body fluid regulation. The blood concentration of BNP is used in human medicine and small animal medicine as a diagnostic tool in the identification of heart diseases and as a prognostic marker for the risk of mortality. The nucleotide and amino acid sequence of BNP was described in Congo (n = 4) and Timneh (n = 3) grey parrots by PCR after RNA isolation from the atria and ventricles. The results showed a high similarity between the nucleotide sequences of the grey parrots’ BNP and the already known sequence of this hormone in chickens. The amino acid sequence of the mature peptide region is consistent in these three species. BNP plasma concentration could be a possible blood parameter for identifying clinically manifest cardiovascular diseases in grey parrots as it is in other species. Springer Netherlands 2021-07-19 2021 /pmc/articles/PMC8626375/ /pubmed/34278549 http://dx.doi.org/10.1007/s11259-021-09813-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Hennig, Anja
Mohr, L.
Fehr, M.
Legler, M.
The B-type natriuretic peptide of the Congo and Timneh grey parrot
title The B-type natriuretic peptide of the Congo and Timneh grey parrot
title_full The B-type natriuretic peptide of the Congo and Timneh grey parrot
title_fullStr The B-type natriuretic peptide of the Congo and Timneh grey parrot
title_full_unstemmed The B-type natriuretic peptide of the Congo and Timneh grey parrot
title_short The B-type natriuretic peptide of the Congo and Timneh grey parrot
title_sort b-type natriuretic peptide of the congo and timneh grey parrot
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626375/
https://www.ncbi.nlm.nih.gov/pubmed/34278549
http://dx.doi.org/10.1007/s11259-021-09813-3
work_keys_str_mv AT henniganja thebtypenatriureticpeptideofthecongoandtimnehgreyparrot
AT mohrl thebtypenatriureticpeptideofthecongoandtimnehgreyparrot
AT fehrm thebtypenatriureticpeptideofthecongoandtimnehgreyparrot
AT leglerm thebtypenatriureticpeptideofthecongoandtimnehgreyparrot
AT henniganja btypenatriureticpeptideofthecongoandtimnehgreyparrot
AT mohrl btypenatriureticpeptideofthecongoandtimnehgreyparrot
AT fehrm btypenatriureticpeptideofthecongoandtimnehgreyparrot
AT leglerm btypenatriureticpeptideofthecongoandtimnehgreyparrot