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The B-type natriuretic peptide of the Congo and Timneh grey parrot
In captivity, cardiovascular diseases are common in grey parrots. The diagnosis of these diseases in living birds is difficult, and new diagnostic possibilities would be desirable. The heart is an important endocrine organ in which cardiomyocytes synthetise B-type natriuretic peptide (BNP) and relea...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626375/ https://www.ncbi.nlm.nih.gov/pubmed/34278549 http://dx.doi.org/10.1007/s11259-021-09813-3 |
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author | Hennig, Anja Mohr, L. Fehr, M. Legler, M. |
author_facet | Hennig, Anja Mohr, L. Fehr, M. Legler, M. |
author_sort | Hennig, Anja |
collection | PubMed |
description | In captivity, cardiovascular diseases are common in grey parrots. The diagnosis of these diseases in living birds is difficult, and new diagnostic possibilities would be desirable. The heart is an important endocrine organ in which cardiomyocytes synthetise B-type natriuretic peptide (BNP) and release it into the bloodstream. This hormone has a significant role in cardiovascular and body fluid regulation. The blood concentration of BNP is used in human medicine and small animal medicine as a diagnostic tool in the identification of heart diseases and as a prognostic marker for the risk of mortality. The nucleotide and amino acid sequence of BNP was described in Congo (n = 4) and Timneh (n = 3) grey parrots by PCR after RNA isolation from the atria and ventricles. The results showed a high similarity between the nucleotide sequences of the grey parrots’ BNP and the already known sequence of this hormone in chickens. The amino acid sequence of the mature peptide region is consistent in these three species. BNP plasma concentration could be a possible blood parameter for identifying clinically manifest cardiovascular diseases in grey parrots as it is in other species. |
format | Online Article Text |
id | pubmed-8626375 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-86263752021-12-01 The B-type natriuretic peptide of the Congo and Timneh grey parrot Hennig, Anja Mohr, L. Fehr, M. Legler, M. Vet Res Commun Original Article In captivity, cardiovascular diseases are common in grey parrots. The diagnosis of these diseases in living birds is difficult, and new diagnostic possibilities would be desirable. The heart is an important endocrine organ in which cardiomyocytes synthetise B-type natriuretic peptide (BNP) and release it into the bloodstream. This hormone has a significant role in cardiovascular and body fluid regulation. The blood concentration of BNP is used in human medicine and small animal medicine as a diagnostic tool in the identification of heart diseases and as a prognostic marker for the risk of mortality. The nucleotide and amino acid sequence of BNP was described in Congo (n = 4) and Timneh (n = 3) grey parrots by PCR after RNA isolation from the atria and ventricles. The results showed a high similarity between the nucleotide sequences of the grey parrots’ BNP and the already known sequence of this hormone in chickens. The amino acid sequence of the mature peptide region is consistent in these three species. BNP plasma concentration could be a possible blood parameter for identifying clinically manifest cardiovascular diseases in grey parrots as it is in other species. Springer Netherlands 2021-07-19 2021 /pmc/articles/PMC8626375/ /pubmed/34278549 http://dx.doi.org/10.1007/s11259-021-09813-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article Hennig, Anja Mohr, L. Fehr, M. Legler, M. The B-type natriuretic peptide of the Congo and Timneh grey parrot |
title | The B-type natriuretic peptide of the Congo and Timneh grey parrot |
title_full | The B-type natriuretic peptide of the Congo and Timneh grey parrot |
title_fullStr | The B-type natriuretic peptide of the Congo and Timneh grey parrot |
title_full_unstemmed | The B-type natriuretic peptide of the Congo and Timneh grey parrot |
title_short | The B-type natriuretic peptide of the Congo and Timneh grey parrot |
title_sort | b-type natriuretic peptide of the congo and timneh grey parrot |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626375/ https://www.ncbi.nlm.nih.gov/pubmed/34278549 http://dx.doi.org/10.1007/s11259-021-09813-3 |
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