BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is a pediatric malignancy of skeletal muscle lineage. The aggressive alveolar subtype is characterized by t(2;13) or t(1;13) translocations encoding for PAX3- or PAX7-FOXO1 chimeric transcription factors, respectively, and are referred to as fusion positive RMS (FP-RMS). The f...

Descripción completa

Detalles Bibliográficos
Autores principales: Laubscher, Dominik, Gryder, Berkley E., Sunkel, Benjamin D., Andresson, Thorkell, Wachtel, Marco, Das, Sudipto, Roschitzki, Bernd, Wolski, Witold, Wu, Xiaoli S., Chou, Hsien-Chao, Song, Young K., Wang, Chaoyu, Wei, Jun S., Wang, Meng, Wen, Xinyu, Ngo, Quy Ai, Marques, Joana G., Vakoc, Christopher R., Schäfer, Beat W., Stanton, Benjamin Z., Khan, Javed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626462/
https://www.ncbi.nlm.nih.gov/pubmed/34836971
http://dx.doi.org/10.1038/s41467-021-27176-w

Ejemplares similares

Ejemplares similares