Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes

Black women across the African diaspora experience more aggressive breast cancer with higher mortality rates than white women of European ancestry. Although inter-ethnic germline variation is known, differential somatic evolution has not been investigated in detail. Analysis of deep whole genomes of...

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Detalles Bibliográficos
Autores principales: Ansari-Pour, Naser, Zheng, Yonglan, Yoshimatsu, Toshio F., Sanni, Ayodele, Ajani, Mustapha, Reynier, Jean-Baptiste, Tapinos, Avraam, Pitt, Jason J., Dentro, Stefan, Woodard, Anna, Rajagopal, Padma Sheila, Fitzgerald, Dominic, Gruber, Andreas J., Odetunde, Abayomi, Popoola, Abiodun, Falusi, Adeyinka G., Babalola, Chinedum Peace, Ogundiran, Temidayo, Ibrahim, Nasiru, Barretina, Jordi, Van Loo, Peter, Chen, Mengjie, White, Kevin P., Ojengbede, Oladosu, Obafunwa, John, Huo, Dezheng, Wedge, David C., Olopade, Olufunmilayo I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626467/
https://www.ncbi.nlm.nih.gov/pubmed/34836952
http://dx.doi.org/10.1038/s41467-021-27079-w

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