Helicobacter pylori FabX contains a [4Fe-4S] cluster essential for unsaturated fatty acid synthesis

Unsaturated fatty acids (UFAs) are essential for functional membrane phospholipids in most bacteria. The bifunctional dehydrogenase/isomerase FabX is an essential UFA biosynthesis enzyme in the widespread human pathogen Helicobacter pylori, a bacterium etiologically related to 95% of gastric cancers...

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Detalles Bibliográficos
Autores principales: Zhou, Jiashen, Zhang, Lin, Zeng, Liping, Yu, Lu, Duan, Yuanyuan, Shen, Siqi, Hu, Jingyan, Zhang, Pan, Song, Wenyan, Ruan, Xiaoxue, Jiang, Jing, Zhang, Yinan, Zhou, Lu, Jia, Jia, Hang, Xudong, Tian, Changlin, Lin, Houwen, Chen, Hong-Zhuan, Cronan, John E., Bi, Hongkai, Zhang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626469/
https://www.ncbi.nlm.nih.gov/pubmed/34836944
http://dx.doi.org/10.1038/s41467-021-27148-0

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