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Cryo-EM snapshots of a native lysate provide structural insights into a metabolon-embedded transacetylase reaction

Found across all kingdoms of life, 2-keto acid dehydrogenase complexes possess prominent metabolic roles and form major regulatory sites. Although their component structures are known, their higher-order organization is highly heterogeneous, not only across species or tissues but also even within a...

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Detalles Bibliográficos
Autores principales: Tüting, Christian, Kyrilis, Fotis L., Müller, Johannes, Sorokina, Marija, Skalidis, Ioannis, Hamdi, Farzad, Sadian, Yashar, Kastritis, Panagiotis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626477/
https://www.ncbi.nlm.nih.gov/pubmed/34836937
http://dx.doi.org/10.1038/s41467-021-27287-4