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Structure of a bacterial α-1,2-glucosidase defines mechanisms of hydrolysis and substrate specificity in GH65 family hydrolases

Glycoside hydrolase family 65 (GH65) comprises glycoside hydrolases (GHs) and glycoside phosphorylases (GPs) that act on α-glucosidic linkages in oligosaccharides. All previously reported bacterial GH65 enzymes are GPs, whereas all eukaryotic GH65 enzymes known are GHs. In addition, to date, no crys...

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Detalles Bibliográficos
Autores principales:	Nakamura, Shuntaro, Nihira, Takanori, Kurata, Rikuya, Nakai, Hiroyuki, Funane, Kazumi, Park, Enoch Y., Miyazaki, Takatsugu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626586/ https://www.ncbi.nlm.nih.gov/pubmed/34728215 http://dx.doi.org/10.1016/j.jbc.2021.101366

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