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Laser-induced ultrasound transmitters for large-volume ultrasound tomography

We present a protocol for the design, fabrication and characterisation of laser-induced ultrasound transmitters with a specific, user-defined frequency response for the purpose of ultrasound tomography of large-volume biomedical samples. Using an analytic solution to the photoacoustic equation and m...

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Detalles Bibliográficos
Autores principales: Thompson, D., Nagel, J.R., Gasteau, D.B., Manohar, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626690/
https://www.ncbi.nlm.nih.gov/pubmed/34868873
http://dx.doi.org/10.1016/j.pacs.2021.100312
Descripción
Sumario:We present a protocol for the design, fabrication and characterisation of laser-induced ultrasound transmitters with a specific, user-defined frequency response for the purpose of ultrasound tomography of large-volume biomedical samples. Using an analytic solution to the photoacoustic equation and measurements of the optical and acoustic properties of the materials used in the transmitters, we arrive at a required mixture of carbon black and polydimethylsiloxane to achieve the desired frequency response. After an in-depth explanation of the fabrication and characterisation approaches we show the performance of the fabricated transmitter, which has a centre frequency of 0.9 MHz, 200% bandwidth and 45.8 [Formula: see text] opening angle, multi-kPa pressures over a large depth range in water.