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Laser-induced ultrasound transmitters for large-volume ultrasound tomography
We present a protocol for the design, fabrication and characterisation of laser-induced ultrasound transmitters with a specific, user-defined frequency response for the purpose of ultrasound tomography of large-volume biomedical samples. Using an analytic solution to the photoacoustic equation and m...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626690/ https://www.ncbi.nlm.nih.gov/pubmed/34868873 http://dx.doi.org/10.1016/j.pacs.2021.100312 |
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author | Thompson, D. Nagel, J.R. Gasteau, D.B. Manohar, S. |
author_facet | Thompson, D. Nagel, J.R. Gasteau, D.B. Manohar, S. |
author_sort | Thompson, D. |
collection | PubMed |
description | We present a protocol for the design, fabrication and characterisation of laser-induced ultrasound transmitters with a specific, user-defined frequency response for the purpose of ultrasound tomography of large-volume biomedical samples. Using an analytic solution to the photoacoustic equation and measurements of the optical and acoustic properties of the materials used in the transmitters, we arrive at a required mixture of carbon black and polydimethylsiloxane to achieve the desired frequency response. After an in-depth explanation of the fabrication and characterisation approaches we show the performance of the fabricated transmitter, which has a centre frequency of 0.9 MHz, 200% bandwidth and 45.8 [Formula: see text] opening angle, multi-kPa pressures over a large depth range in water. |
format | Online Article Text |
id | pubmed-8626690 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-86266902021-12-02 Laser-induced ultrasound transmitters for large-volume ultrasound tomography Thompson, D. Nagel, J.R. Gasteau, D.B. Manohar, S. Photoacoustics Research Article We present a protocol for the design, fabrication and characterisation of laser-induced ultrasound transmitters with a specific, user-defined frequency response for the purpose of ultrasound tomography of large-volume biomedical samples. Using an analytic solution to the photoacoustic equation and measurements of the optical and acoustic properties of the materials used in the transmitters, we arrive at a required mixture of carbon black and polydimethylsiloxane to achieve the desired frequency response. After an in-depth explanation of the fabrication and characterisation approaches we show the performance of the fabricated transmitter, which has a centre frequency of 0.9 MHz, 200% bandwidth and 45.8 [Formula: see text] opening angle, multi-kPa pressures over a large depth range in water. Elsevier 2021-11-10 /pmc/articles/PMC8626690/ /pubmed/34868873 http://dx.doi.org/10.1016/j.pacs.2021.100312 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Research Article Thompson, D. Nagel, J.R. Gasteau, D.B. Manohar, S. Laser-induced ultrasound transmitters for large-volume ultrasound tomography |
title | Laser-induced ultrasound transmitters for large-volume ultrasound tomography |
title_full | Laser-induced ultrasound transmitters for large-volume ultrasound tomography |
title_fullStr | Laser-induced ultrasound transmitters for large-volume ultrasound tomography |
title_full_unstemmed | Laser-induced ultrasound transmitters for large-volume ultrasound tomography |
title_short | Laser-induced ultrasound transmitters for large-volume ultrasound tomography |
title_sort | laser-induced ultrasound transmitters for large-volume ultrasound tomography |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626690/ https://www.ncbi.nlm.nih.gov/pubmed/34868873 http://dx.doi.org/10.1016/j.pacs.2021.100312 |
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