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Laser-induced ultrasound transmitters for large-volume ultrasound tomography

We present a protocol for the design, fabrication and characterisation of laser-induced ultrasound transmitters with a specific, user-defined frequency response for the purpose of ultrasound tomography of large-volume biomedical samples. Using an analytic solution to the photoacoustic equation and m...

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Detalles Bibliográficos
Autores principales: Thompson, D., Nagel, J.R., Gasteau, D.B., Manohar, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626690/
https://www.ncbi.nlm.nih.gov/pubmed/34868873
http://dx.doi.org/10.1016/j.pacs.2021.100312
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author Thompson, D.
Nagel, J.R.
Gasteau, D.B.
Manohar, S.
author_facet Thompson, D.
Nagel, J.R.
Gasteau, D.B.
Manohar, S.
author_sort Thompson, D.
collection PubMed
description We present a protocol for the design, fabrication and characterisation of laser-induced ultrasound transmitters with a specific, user-defined frequency response for the purpose of ultrasound tomography of large-volume biomedical samples. Using an analytic solution to the photoacoustic equation and measurements of the optical and acoustic properties of the materials used in the transmitters, we arrive at a required mixture of carbon black and polydimethylsiloxane to achieve the desired frequency response. After an in-depth explanation of the fabrication and characterisation approaches we show the performance of the fabricated transmitter, which has a centre frequency of 0.9 MHz, 200% bandwidth and 45.8 [Formula: see text] opening angle, multi-kPa pressures over a large depth range in water.
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spelling pubmed-86266902021-12-02 Laser-induced ultrasound transmitters for large-volume ultrasound tomography Thompson, D. Nagel, J.R. Gasteau, D.B. Manohar, S. Photoacoustics Research Article We present a protocol for the design, fabrication and characterisation of laser-induced ultrasound transmitters with a specific, user-defined frequency response for the purpose of ultrasound tomography of large-volume biomedical samples. Using an analytic solution to the photoacoustic equation and measurements of the optical and acoustic properties of the materials used in the transmitters, we arrive at a required mixture of carbon black and polydimethylsiloxane to achieve the desired frequency response. After an in-depth explanation of the fabrication and characterisation approaches we show the performance of the fabricated transmitter, which has a centre frequency of 0.9 MHz, 200% bandwidth and 45.8 [Formula: see text] opening angle, multi-kPa pressures over a large depth range in water. Elsevier 2021-11-10 /pmc/articles/PMC8626690/ /pubmed/34868873 http://dx.doi.org/10.1016/j.pacs.2021.100312 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Research Article
Thompson, D.
Nagel, J.R.
Gasteau, D.B.
Manohar, S.
Laser-induced ultrasound transmitters for large-volume ultrasound tomography
title Laser-induced ultrasound transmitters for large-volume ultrasound tomography
title_full Laser-induced ultrasound transmitters for large-volume ultrasound tomography
title_fullStr Laser-induced ultrasound transmitters for large-volume ultrasound tomography
title_full_unstemmed Laser-induced ultrasound transmitters for large-volume ultrasound tomography
title_short Laser-induced ultrasound transmitters for large-volume ultrasound tomography
title_sort laser-induced ultrasound transmitters for large-volume ultrasound tomography
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626690/
https://www.ncbi.nlm.nih.gov/pubmed/34868873
http://dx.doi.org/10.1016/j.pacs.2021.100312
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