Ligand-Independent G Protein–Coupled Estrogen Receptor/G Protein–Coupled Receptor 30 Activity: Lack of Receptor-Dependent Effects of G-1 and 17β-Estradiol

G protein–coupled receptor 30 (GPR30) is a membrane receptor reported to bind 17β-estradiol (E2) and mediate rapid nongenomic estrogen responses, hence also named G protein–coupled estrogen receptor. G-1 is a proposed GPR30-specific agonist that has been used to implicate the receptor in several pat...

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Detalles Bibliográficos
Autores principales: Tutzauer, Julia, Gonzalez de Valdivia, Ernesto, Swärd, Karl, Alexandrakis Eilard, Ioannis, Broselid, Stefan, Kahn, Robin, Olde, Björn, Leeb-Lundberg, L. M. Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626787/
https://www.ncbi.nlm.nih.gov/pubmed/34330822
http://dx.doi.org/10.1124/molpharm.121.000259

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