Role of the Phospholipase C Pathway and Calcium Mobilization in Oxytocin-Induced Contraction of Lacrimal Gland Myoepithelial Cells

PURPOSE: We reported that oxytocin (OXT), added to freshly prepared lacrimal gland lobules, induced myoepithelial cell (MEC) contraction. In other systems, OXT activates phospholipase C (PLC) generating Inositol 1,4,5-trisphosphate (IP(3)) which increases intracellular calcium concentration ([Ca(2+)...

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Detalles Bibliográficos
Autores principales: Gárriz, Angela, Aubry, Salome, Wattiaux, Quentin, Bair, Jeffrey, Mariano, Michael, Hatzipetrou, Georgios, Bowman, Maytal, Morokuma, Junji, Ortiz, Gustavo, Hamrah, Pedram, Dartt, Darlene A., Zoukhri, Driss
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626846/
https://www.ncbi.nlm.nih.gov/pubmed/34812841
http://dx.doi.org/10.1167/iovs.62.14.25

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