Inhibition of Sema-3A Promotes Cell Migration, Axonal Growth, and Retinal Ganglion Cell Survival

PURPOSE: Semaphorin 3A (Sema-3A) is a secreted protein that deflects axons from inappropriate regions and induces neuronal cell death. Intravitreal application of polyclonal antibodies against Sema-3A prevents loss of retinal ganglion cells ensuing from axotomy of optic nerves. This suggested a ther...

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Detalles Bibliográficos
Autores principales: Nitzan, Anat, Corredor-Sanchez, Miriam, Galron, Ronit, Nahary, Limor, Safrin, Mary, Bruzel, Marina, Moure, Alejandra, Bonet, Roman, Pérez, Yolanda, Bujons, Jordi, Vallejo-Yague, Enriqueta, Sacks, Hagit, Burnet, Michael, Alfonso, Ignacio, Messeguer, Angel, Benhar, Itai, Barzilai, Ari, Solomon, Arieh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Special Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626852/
https://www.ncbi.nlm.nih.gov/pubmed/34817617
http://dx.doi.org/10.1167/tvst.10.10.16

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