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Conditional Deletion of Cytoplasmic Dynein Heavy Chain in Postnatal Photoreceptors

PURPOSE: Cytoplasmic dynein-1 (henceforth dynein) moves cargo in conjunction with dynactin toward the minus end of microtubules. The dynein heavy chain, DYNC1H1, comprises the backbone of dynein, a retrograde motor. Deletion of Dync1h1 abrogates dynein function. The purpose of this communication is...

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Detalles Bibliográficos
Autores principales:	Dahl, Tiffanie M., Reed, Michelle, Gerstner, Cecilia D., Baehr, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2021
Materias:	Biochemistry and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626856/ https://www.ncbi.nlm.nih.gov/pubmed/34807236 http://dx.doi.org/10.1167/iovs.62.14.23

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