Detection and phylogenetic analysis of a novel tick-borne virus in Haemaphysalis longicornis ticks and sheep from Shandong, China

Dabieshan tick virus (DTV) was first identified in Haemaphysalis longicornis from Hubei Province, China in 2015. However, its pathogenic potential to animals and human remains to be further explored. In this study, a total of 170 engorged ticks and 22 sheep serum samples were collected from Taian an...

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Autores principales: Shao, Lijun, Chang, Ruiheng, Liu, Lin, Wang, Yongjin, Gao, Yun, Wang, Shaoqing, Sun, Hengyi, Niu, Guoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626915/
https://www.ncbi.nlm.nih.gov/pubmed/34838085
http://dx.doi.org/10.1186/s12985-021-01704-y
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author Shao, Lijun
Chang, Ruiheng
Liu, Lin
Wang, Yongjin
Gao, Yun
Wang, Shaoqing
Sun, Hengyi
Niu, Guoyu
author_facet Shao, Lijun
Chang, Ruiheng
Liu, Lin
Wang, Yongjin
Gao, Yun
Wang, Shaoqing
Sun, Hengyi
Niu, Guoyu
author_sort Shao, Lijun
collection PubMed
description Dabieshan tick virus (DTV) was first identified in Haemaphysalis longicornis from Hubei Province, China in 2015. However, its pathogenic potential to animals and human remains to be further explored. In this study, a total of 170 engorged ticks and 22 sheep serum samples were collected from Taian and Yantai city, Shandong Province to investigate the presence of DTV. The results of qRT-PCR revealed the positive rate of 13.6% (3/22) in sheep serum and 8.2% (14/170) in attached ticks, respectively. Phylogenetic analysis demonstrated a close evolutionary relationship among those DTV isolates from animal and ticks, and DTV might be relatively conservative in evolution. These findings are the first to demonstrate molecular evidence of DTV in domestic animals. Nonetheless, whether or not causing disease in animals, DTV deserves further investigation.
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spelling pubmed-86269152021-11-29 Detection and phylogenetic analysis of a novel tick-borne virus in Haemaphysalis longicornis ticks and sheep from Shandong, China Shao, Lijun Chang, Ruiheng Liu, Lin Wang, Yongjin Gao, Yun Wang, Shaoqing Sun, Hengyi Niu, Guoyu Virol J Short Report Dabieshan tick virus (DTV) was first identified in Haemaphysalis longicornis from Hubei Province, China in 2015. However, its pathogenic potential to animals and human remains to be further explored. In this study, a total of 170 engorged ticks and 22 sheep serum samples were collected from Taian and Yantai city, Shandong Province to investigate the presence of DTV. The results of qRT-PCR revealed the positive rate of 13.6% (3/22) in sheep serum and 8.2% (14/170) in attached ticks, respectively. Phylogenetic analysis demonstrated a close evolutionary relationship among those DTV isolates from animal and ticks, and DTV might be relatively conservative in evolution. These findings are the first to demonstrate molecular evidence of DTV in domestic animals. Nonetheless, whether or not causing disease in animals, DTV deserves further investigation. BioMed Central 2021-11-27 /pmc/articles/PMC8626915/ /pubmed/34838085 http://dx.doi.org/10.1186/s12985-021-01704-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Short Report
Shao, Lijun
Chang, Ruiheng
Liu, Lin
Wang, Yongjin
Gao, Yun
Wang, Shaoqing
Sun, Hengyi
Niu, Guoyu
Detection and phylogenetic analysis of a novel tick-borne virus in Haemaphysalis longicornis ticks and sheep from Shandong, China
title Detection and phylogenetic analysis of a novel tick-borne virus in Haemaphysalis longicornis ticks and sheep from Shandong, China
title_full Detection and phylogenetic analysis of a novel tick-borne virus in Haemaphysalis longicornis ticks and sheep from Shandong, China
title_fullStr Detection and phylogenetic analysis of a novel tick-borne virus in Haemaphysalis longicornis ticks and sheep from Shandong, China
title_full_unstemmed Detection and phylogenetic analysis of a novel tick-borne virus in Haemaphysalis longicornis ticks and sheep from Shandong, China
title_short Detection and phylogenetic analysis of a novel tick-borne virus in Haemaphysalis longicornis ticks and sheep from Shandong, China
title_sort detection and phylogenetic analysis of a novel tick-borne virus in haemaphysalis longicornis ticks and sheep from shandong, china
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626915/
https://www.ncbi.nlm.nih.gov/pubmed/34838085
http://dx.doi.org/10.1186/s12985-021-01704-y
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