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Downregulation of miR-29c promotes muscle wasting by modulating the activity of leukemia inhibitory factor in lung cancer cachexia

BACKGROUND: Cancer cachexia is a wasting disorder characterized by significant weight loss, and is attributed to skeletal muscle weakness. In the process of cancer development, microRNAs act as oncogenes or tumor suppressors. Moreover, they are implicated in muscle development and wasting. This stud...

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Detalles Bibliográficos
Autores principales: Xie, Kairu, Xiong, Hairong, Xiao, Wen, Xiong, Zhiyong, Hu, Wenjun, Ye, Jiaxin, Xu, Ning, Shi, Jian, Yuan, Changfei, Chen, Zhixian, Miao, Daojia, Zhang, Xiaoping, Yang, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626920/
https://www.ncbi.nlm.nih.gov/pubmed/34838029
http://dx.doi.org/10.1186/s12935-021-02332-w

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