MicroRNA-100-5p and microRNA-298-5p released from apoptotic cortical neurons are endogenous Toll-like receptor 7/8 ligands that contribute to neurodegeneration

BACKGROUND: MicroRNA (miRNA) expression in the brain is altered in neurodegenerative diseases. Recent studies demonstrated that selected miRNAs conventionally regulating gene expression at the post-transcriptional level can act extracellularly as signaling molecules. The identity of miRNA species se...

Descripción completa

Detalles Bibliográficos
Autores principales: Wallach, Thomas, Mossmann, Zoé J., Szczepek, Michal, Wetzel, Max, Machado, Rui, Raden, Martin, Miladi, Milad, Kleinau, Gunnar, Krüger, Christina, Dembny, Paul, Adler, Drew, Zhai, Yuanyuan, Kumbol, Victor, Dzaye, Omar, Schüler, Jutta, Futschik, Matthias, Backofen, Rolf, Scheerer, Patrick, Lehnardt, Seija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626928/
https://www.ncbi.nlm.nih.gov/pubmed/34838071
http://dx.doi.org/10.1186/s13024-021-00498-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626928/
https://www.ncbi.nlm.nih.gov/pubmed/34838071
http://dx.doi.org/10.1186/s13024-021-00498-5

Ejemplares similares