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Bone morphogenetic protein 2 inhibits growth differentiation factor 8-induced cell signaling via upregulation of gremlin2 expression in human granulosa-lutein cells

BACKGROUND: Bone morphogenetic protein 2 (BMP2), growth differentiation factor 8 (GDF8) and their functional receptors are expressed in human ovarian follicles, and these two intrafollicular factors play essential roles in regulating follicle development and luteal function. As BMP antagonists, grem...

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Detalles Bibliográficos
Autores principales: Luo, Xiaoyan, Chang, Hsun-Ming, Yi, Yuyin, Sun, Yingpu, Leung, Peter C. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626944/
https://www.ncbi.nlm.nih.gov/pubmed/34838049
http://dx.doi.org/10.1186/s12958-021-00854-6