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Bone morphogenetic protein 2 inhibits growth differentiation factor 8-induced cell signaling via upregulation of gremlin2 expression in human granulosa-lutein cells
BACKGROUND: Bone morphogenetic protein 2 (BMP2), growth differentiation factor 8 (GDF8) and their functional receptors are expressed in human ovarian follicles, and these two intrafollicular factors play essential roles in regulating follicle development and luteal function. As BMP antagonists, grem...
Autores principales: | Luo, Xiaoyan, Chang, Hsun-Ming, Yi, Yuyin, Sun, Yingpu, Leung, Peter C. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626944/ https://www.ncbi.nlm.nih.gov/pubmed/34838049 http://dx.doi.org/10.1186/s12958-021-00854-6 |
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