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NEDD4L-induced ubiquitination mediating UBE2T degradation inhibits progression of lung adenocarcinoma via PI3K-AKT signaling

BACKGROUND: A number of studies have indicated that Ubiquitin-conjugating enzyme E2T (UBE2T), as an oncogene, promotes progression and metastasis of lung cancer, including lung adenocarcinoma (LUAD), but it is completely unknown whether and how UBE2T is ubiquitylated and degraded, and by which E3 li...

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Detalles Bibliográficos
Autores principales:	Chen, Yongbing, Hong, Haihua, Wang, Qingqing, Li, Junqiang, Zhang, Wenfeng, Chen, Tingting, Li, Pu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626996/ https://www.ncbi.nlm.nih.gov/pubmed/34838005 http://dx.doi.org/10.1186/s12935-021-02341-9

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