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Host parameters and mode of infection influence outcome in SARS-CoV-2-infected hamsters

The golden hamster model of SARS-CoV-2 infection recapitulates key characteristics of COVID-19. In this work we examined the influence of the route of exposure, sex, and age on SARS-CoV-2 pathogenesis in hamsters. We report that delivery of SARS-CoV-2 by a low- versus high-volume intranasal or intra...

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Detalles Bibliográficos
Autores principales:	Griffin, Bryan D., Warner, Bryce M., Chan, Mable, Valcourt, Emelissa, Tailor, Nikesh, Banadyga, Logan, Leung, Anders, He, Shihua, Boese, Amrit S., Audet, Jonathan, Cao, Wenguang, Moffat, Estella, Garnett, Lauren, Tierney, Kevin, Tran, Kaylie N., Albietz, Alixandra, Manguiat, Kathy, Soule, Geoff, Bello, Alexander, Vendramelli, Robert, Lin, Jessica, Deschambault, Yvon, Zhu, Wenjun, Wood, Heidi, Mubareka, Samira, Safronetz, David, Strong, James E., Embury-Hyatt, Carissa, Kobasa, Darwyn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627009/ https://www.ncbi.nlm.nih.gov/pubmed/34870132 http://dx.doi.org/10.1016/j.isci.2021.103530

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