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Amplification of spatially isolated adenosine pathway by tumor–macrophage interaction induces anti-PD1 resistance in hepatocellular carcinoma

BACKGROUND: Immune checkpoint blockade resistance narrows the efficacy of cancer immunotherapies, but the underlying mechanism remains elusive. Delineating the inherent mechanisms of anti-PD1 resistance is important to improve outcome of patients with advanced HCC. METHOD: The level of cricTMEM181 w...

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Detalles Bibliográficos
Autores principales:	Lu, Jia-Cheng, Zhang, Peng-Fei, Huang, Xiao-Yong, Guo, Xiao-Jun, Gao, Chao, Zeng, Hai-Ying, Zheng, Yi-Min, Wang, Si-Wei, Cai, Jia-Bin, Sun, Qi-Man, Shi, Ying-Hong, Zhou, Jian, Ke, Ai-Wu, Shi, Guo-Ming, Fan, Jia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627086/ https://www.ncbi.nlm.nih.gov/pubmed/34838121 http://dx.doi.org/10.1186/s13045-021-01207-x

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