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Mathematical modeling and optimal control of the COVID-19 dynamics

We are considering a new COVID-19 model with an optimal control analysis when vaccination is present. Firstly, we formulate the vaccine-free model and present the associated mathematical results involved. Stability results for [Formula: see text] are shown. In addition, we frame the model with the v...

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Autores principales: Shen, Zhong-Hua, Chu, Yu-Ming, Khan, Muhammad Altaf, Muhammad, Shabbir, Al-Hartomy, Omar A., Higazy, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627298/
https://www.ncbi.nlm.nih.gov/pubmed/34868832
http://dx.doi.org/10.1016/j.rinp.2021.105028
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author Shen, Zhong-Hua
Chu, Yu-Ming
Khan, Muhammad Altaf
Muhammad, Shabbir
Al-Hartomy, Omar A.
Higazy, M.
author_facet Shen, Zhong-Hua
Chu, Yu-Ming
Khan, Muhammad Altaf
Muhammad, Shabbir
Al-Hartomy, Omar A.
Higazy, M.
author_sort Shen, Zhong-Hua
collection PubMed
description We are considering a new COVID-19 model with an optimal control analysis when vaccination is present. Firstly, we formulate the vaccine-free model and present the associated mathematical results involved. Stability results for [Formula: see text] are shown. In addition, we frame the model with the vaccination class. We look at the mathematical results with the details of the vaccine model. Additionally, we are considering setting controls to minimize infection spread and control. We consider four different controls, such as prevention, vaccination control, rapid screening of people in the exposed category, and people who are identified as infected without screening. Using the suggested controls, we develop an optimal control model and derive mathematical results from it. In addition, the mathematical model with control and without control is resolved by the forward–backward Runge–Kutta method and presents the results graphically. The results obtained through optimal control suggest that controls can be useful for minimizing infected individuals and improving population health.
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spelling pubmed-86272982021-11-29 Mathematical modeling and optimal control of the COVID-19 dynamics Shen, Zhong-Hua Chu, Yu-Ming Khan, Muhammad Altaf Muhammad, Shabbir Al-Hartomy, Omar A. Higazy, M. Results Phys Article We are considering a new COVID-19 model with an optimal control analysis when vaccination is present. Firstly, we formulate the vaccine-free model and present the associated mathematical results involved. Stability results for [Formula: see text] are shown. In addition, we frame the model with the vaccination class. We look at the mathematical results with the details of the vaccine model. Additionally, we are considering setting controls to minimize infection spread and control. We consider four different controls, such as prevention, vaccination control, rapid screening of people in the exposed category, and people who are identified as infected without screening. Using the suggested controls, we develop an optimal control model and derive mathematical results from it. In addition, the mathematical model with control and without control is resolved by the forward–backward Runge–Kutta method and presents the results graphically. The results obtained through optimal control suggest that controls can be useful for minimizing infected individuals and improving population health. The Authors. Published by Elsevier B.V. 2021-12 2021-11-27 /pmc/articles/PMC8627298/ /pubmed/34868832 http://dx.doi.org/10.1016/j.rinp.2021.105028 Text en © 2021 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Shen, Zhong-Hua
Chu, Yu-Ming
Khan, Muhammad Altaf
Muhammad, Shabbir
Al-Hartomy, Omar A.
Higazy, M.
Mathematical modeling and optimal control of the COVID-19 dynamics
title Mathematical modeling and optimal control of the COVID-19 dynamics
title_full Mathematical modeling and optimal control of the COVID-19 dynamics
title_fullStr Mathematical modeling and optimal control of the COVID-19 dynamics
title_full_unstemmed Mathematical modeling and optimal control of the COVID-19 dynamics
title_short Mathematical modeling and optimal control of the COVID-19 dynamics
title_sort mathematical modeling and optimal control of the covid-19 dynamics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627298/
https://www.ncbi.nlm.nih.gov/pubmed/34868832
http://dx.doi.org/10.1016/j.rinp.2021.105028
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