Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial

RESULTS: There were a total of 60 patients who were followed up. Three patients in Group II were removed from the analysis as they underwent total knee arthroplasty (TKA). A notably significant improvement was noticed in the ABMDC group on all scores of VAS and MKSSSF with P < 0.0001. The control...

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Autores principales: Sadat-Ali, Mir, AlOmran, Abdallah S., AlMousa, Sulaiman A., AlSayed, Hasan N., AlTabash, Khalid W., Azam, Mohammed Q., Hegazi, Tarek M., Acharya, Sadananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627347/
https://www.ncbi.nlm.nih.gov/pubmed/34845428
http://dx.doi.org/10.1155/2021/2146722
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author Sadat-Ali, Mir
AlOmran, Abdallah S.
AlMousa, Sulaiman A.
AlSayed, Hasan N.
AlTabash, Khalid W.
Azam, Mohammed Q.
Hegazi, Tarek M.
Acharya, Sadananda
author_facet Sadat-Ali, Mir
AlOmran, Abdallah S.
AlMousa, Sulaiman A.
AlSayed, Hasan N.
AlTabash, Khalid W.
Azam, Mohammed Q.
Hegazi, Tarek M.
Acharya, Sadananda
author_sort Sadat-Ali, Mir
collection PubMed
description RESULTS: There were a total of 60 patients who were followed up. Three patients in Group II were removed from the analysis as they underwent total knee arthroplasty (TKA). A notably significant improvement was noticed in the ABMDC group on all scores of VAS and MKSSSF with P < 0.0001. The control group continued to be dissatisfied with the treatment they were taking. CONCLUSIONS: This study reveals that a single injection of 5 million of ABMDC was efficient in reducing the symptoms, improving the functional score and betterment of QOL.
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spelling pubmed-86273472021-11-28 Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial Sadat-Ali, Mir AlOmran, Abdallah S. AlMousa, Sulaiman A. AlSayed, Hasan N. AlTabash, Khalid W. Azam, Mohammed Q. Hegazi, Tarek M. Acharya, Sadananda Adv Orthop Research Article RESULTS: There were a total of 60 patients who were followed up. Three patients in Group II were removed from the analysis as they underwent total knee arthroplasty (TKA). A notably significant improvement was noticed in the ABMDC group on all scores of VAS and MKSSSF with P < 0.0001. The control group continued to be dissatisfied with the treatment they were taking. CONCLUSIONS: This study reveals that a single injection of 5 million of ABMDC was efficient in reducing the symptoms, improving the functional score and betterment of QOL. Hindawi 2021-11-20 /pmc/articles/PMC8627347/ /pubmed/34845428 http://dx.doi.org/10.1155/2021/2146722 Text en Copyright © 2021 Mir Sadat-Ali et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Sadat-Ali, Mir
AlOmran, Abdallah S.
AlMousa, Sulaiman A.
AlSayed, Hasan N.
AlTabash, Khalid W.
Azam, Mohammed Q.
Hegazi, Tarek M.
Acharya, Sadananda
Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial
title Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial
title_full Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial
title_fullStr Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial
title_full_unstemmed Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial
title_short Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial
title_sort autologous bone marrow-derived chondrocytes for patients with knee osteoarthritis: a randomized controlled trial
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627347/
https://www.ncbi.nlm.nih.gov/pubmed/34845428
http://dx.doi.org/10.1155/2021/2146722
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