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Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam

OBJECTIVES: Men who have sex with men (MSM) are at risk of human papillomavirus (HPV)-related cancers, while published data are scarce. This study determined HPV prevalence and risk factors in MSM in Vietnam to inform HPV prevention strategies in this key population. METHODS: A cross-sectional study...

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Autores principales: Tuan, Le Anh, Prem, Kiesha, Pham, Quang Duy, Toh, Zheng Quan, Tran, Hau Phuc, Nguyen, Phuc Duy, Mai, Chu Thi Ngoc, Ly, Le Thi Khanh, Cao, Van, Le-Ha, Tam-Duong, Tuan, Nguyen Anh, Jit, Mark, Bright, Kathryn, Brisson, Marc, Nguyen, Thuong Vu, Garland, Suzanne, Anh, Dang Duc, Trang, Nguyen Van, Mulholland, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627386/
https://www.ncbi.nlm.nih.gov/pubmed/34517047
http://dx.doi.org/10.1016/j.ijid.2021.09.016
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author Tuan, Le Anh
Prem, Kiesha
Pham, Quang Duy
Toh, Zheng Quan
Tran, Hau Phuc
Nguyen, Phuc Duy
Mai, Chu Thi Ngoc
Ly, Le Thi Khanh
Cao, Van
Le-Ha, Tam-Duong
Tuan, Nguyen Anh
Jit, Mark
Bright, Kathryn
Brisson, Marc
Nguyen, Thuong Vu
Garland, Suzanne
Anh, Dang Duc
Trang, Nguyen Van
Mulholland, Kim
author_facet Tuan, Le Anh
Prem, Kiesha
Pham, Quang Duy
Toh, Zheng Quan
Tran, Hau Phuc
Nguyen, Phuc Duy
Mai, Chu Thi Ngoc
Ly, Le Thi Khanh
Cao, Van
Le-Ha, Tam-Duong
Tuan, Nguyen Anh
Jit, Mark
Bright, Kathryn
Brisson, Marc
Nguyen, Thuong Vu
Garland, Suzanne
Anh, Dang Duc
Trang, Nguyen Van
Mulholland, Kim
author_sort Tuan, Le Anh
collection PubMed
description OBJECTIVES: Men who have sex with men (MSM) are at risk of human papillomavirus (HPV)-related cancers, while published data are scarce. This study determined HPV prevalence and risk factors in MSM in Vietnam to inform HPV prevention strategies in this key population. METHODS: A cross-sectional study of 799 MSM aged 16-50 years was conducted in Vietnam in 2017-2018. Information was collected on risk behaviours, and knowledge of HPV and anal cancer; rectal swabs were taken to detect anal HPV infection. An in-house polymerase chain reaction and Genoflow HPV array test kit were used for HPV detection and genotyping. RESULTS: The median age of the study participants was 25 years (range 18-52). Overall prevalence of any HPV and HPV16/18 infection was 32.3% and 11.0%, respectively. A higher prevalence of high-risk HPV infection to all 14 types tested was found in Ho Chi Minh City (30.9%) than in Hanoi (18.4%). High-risk HPV infection was associated with inconsistent condom use and history of engaging in sex under the influence of drugs (adjusted odds ratio (aOR), 2.27; 95% CI, 1.48-10.67), as well as having multiple sexual partners (aOR, 1.01; 95% CI, 1.00–1.02). CONCLUSIONS: High-risk anal HPV infections in Vietnamese MSM were significantly associated with risky sexual behaviours. A targeted HPV vaccination strategy would have substantial benefit for MSM in Vietnam.
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spelling pubmed-86273862021-12-03 Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam Tuan, Le Anh Prem, Kiesha Pham, Quang Duy Toh, Zheng Quan Tran, Hau Phuc Nguyen, Phuc Duy Mai, Chu Thi Ngoc Ly, Le Thi Khanh Cao, Van Le-Ha, Tam-Duong Tuan, Nguyen Anh Jit, Mark Bright, Kathryn Brisson, Marc Nguyen, Thuong Vu Garland, Suzanne Anh, Dang Duc Trang, Nguyen Van Mulholland, Kim Int J Infect Dis Article OBJECTIVES: Men who have sex with men (MSM) are at risk of human papillomavirus (HPV)-related cancers, while published data are scarce. This study determined HPV prevalence and risk factors in MSM in Vietnam to inform HPV prevention strategies in this key population. METHODS: A cross-sectional study of 799 MSM aged 16-50 years was conducted in Vietnam in 2017-2018. Information was collected on risk behaviours, and knowledge of HPV and anal cancer; rectal swabs were taken to detect anal HPV infection. An in-house polymerase chain reaction and Genoflow HPV array test kit were used for HPV detection and genotyping. RESULTS: The median age of the study participants was 25 years (range 18-52). Overall prevalence of any HPV and HPV16/18 infection was 32.3% and 11.0%, respectively. A higher prevalence of high-risk HPV infection to all 14 types tested was found in Ho Chi Minh City (30.9%) than in Hanoi (18.4%). High-risk HPV infection was associated with inconsistent condom use and history of engaging in sex under the influence of drugs (adjusted odds ratio (aOR), 2.27; 95% CI, 1.48-10.67), as well as having multiple sexual partners (aOR, 1.01; 95% CI, 1.00–1.02). CONCLUSIONS: High-risk anal HPV infections in Vietnamese MSM were significantly associated with risky sexual behaviours. A targeted HPV vaccination strategy would have substantial benefit for MSM in Vietnam. Elsevier 2021-11 /pmc/articles/PMC8627386/ /pubmed/34517047 http://dx.doi.org/10.1016/j.ijid.2021.09.016 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Tuan, Le Anh
Prem, Kiesha
Pham, Quang Duy
Toh, Zheng Quan
Tran, Hau Phuc
Nguyen, Phuc Duy
Mai, Chu Thi Ngoc
Ly, Le Thi Khanh
Cao, Van
Le-Ha, Tam-Duong
Tuan, Nguyen Anh
Jit, Mark
Bright, Kathryn
Brisson, Marc
Nguyen, Thuong Vu
Garland, Suzanne
Anh, Dang Duc
Trang, Nguyen Van
Mulholland, Kim
Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam
title Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam
title_full Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam
title_fullStr Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam
title_full_unstemmed Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam
title_short Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam
title_sort anal human papillomavirus prevalence and risk factors among men who have sex with men in vietnam
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627386/
https://www.ncbi.nlm.nih.gov/pubmed/34517047
http://dx.doi.org/10.1016/j.ijid.2021.09.016
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