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Characterizing the molecular composition and diagnostic potential of Mycobacterium tuberculosis urinary cell-free DNA using next-generation sequencing

BACKGROUND: Urine cell-free DNA (cfDNA) is an attractive target for diagnosing pulmonary Mycobacterium tuberculosis (MTB) infection, but has not been thoroughly characterized as a biomarker. METHODS: This study was performed to investigate the size and composition of urine cfDNA from tuberculosis (T...

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Detalles Bibliográficos
Autores principales:	Oreskovic, Amy, Waalkes, Adam, Holmes, Elizabeth A., Rosenthal, Christopher A., Wilson, Douglas P.K., Shapiro, Adrienne E., Drain, Paul K., Lutz, Barry R., Salipante, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627387/ https://www.ncbi.nlm.nih.gov/pubmed/34562627 http://dx.doi.org/10.1016/j.ijid.2021.09.042

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