Maximizing cancer therapy via complementary mechanisms of immune activation: PD-1 blockade, neoantigen vaccination, and Tregs depletion

BACKGROUND: A number of different immune pathways are involved in the effective killing of cancer cells, collectively named as the ‘Cancer Immunity Cycle’. Anti-PD-1 checkpoint blockade (CPB) therapy is active on one of these pathways and reinvigorates anticancer T cell immunity, leading to long-ter...

Descripción completa

Detalles Bibliográficos
Autores principales: D'Alise, Anna Morena, Leoni, Guido, De Lucia, Maria, Langone, Francesca, Nocchi, Linda, Tucci, Fabio Giovanni, Micarelli, Elisa, Cotugno, Gabriella, Troise, Fulvia, Garzia, Irene, Vitale, Rosa, Bignone, Veronica, Di Matteo, Elena, Bartolomeo, Rosa, Charych, Deborah H, Lahm, Armin, Zalevsky, Jonathan, Nicosia, Alfredo, Scarselli, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627409/
https://www.ncbi.nlm.nih.gov/pubmed/34824160
http://dx.doi.org/10.1136/jitc-2021-003480

Ejemplares similares

Ejemplares similares