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MLK4 regulates DNA damage response and promotes triple-negative breast cancer chemoresistance

Chemoresistance constitutes a major challenge in the treatment of triple-negative breast cancer (TNBC). Mixed-Lineage Kinase 4 (MLK4) is frequently amplified or overexpressed in TNBC where it facilitates the aggressive growth and migratory potential of breast cancer cells. However, the functional ro...

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Detalles Bibliográficos
Autores principales:	Mehlich, Dawid, Łomiak, Michał, Sobiborowicz, Aleksandra, Mazan, Alicja, Dymerska, Dagmara, Szewczyk, Łukasz M., Mehlich, Anna, Borowiec, Agnieszka, Prełowska, Monika K., Gorczyński, Adam, Jabłoński, Paweł, Iżycka-Świeszewska, Ewa, Nowis, Dominika, Marusiak, Anna A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627512/ https://www.ncbi.nlm.nih.gov/pubmed/34839359 http://dx.doi.org/10.1038/s41419-021-04405-0

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