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Co-translational biogenesis of lipid droplet integral membrane proteins

Membrane proteins destined for lipid droplets (LDs), a major intracellular storage site for neutral lipids, are inserted into the endoplasmic reticulum (ER) and then trafficked to LDs where they reside in a hairpin loop conformation. Here, we show that LD membrane proteins can be delivered to the ER...

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Detalles Bibliográficos
Autores principales: Leznicki, Pawel, Schneider, Hayden O., Harvey, Jada V., Shi, Wei Q., High, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627552/
https://www.ncbi.nlm.nih.gov/pubmed/34558621
http://dx.doi.org/10.1242/jcs.259220