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Co-translational biogenesis of lipid droplet integral membrane proteins
Membrane proteins destined for lipid droplets (LDs), a major intracellular storage site for neutral lipids, are inserted into the endoplasmic reticulum (ER) and then trafficked to LDs where they reside in a hairpin loop conformation. Here, we show that LD membrane proteins can be delivered to the ER...
Autores principales: | Leznicki, Pawel, Schneider, Hayden O., Harvey, Jada V., Shi, Wei Q., High, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627552/ https://www.ncbi.nlm.nih.gov/pubmed/34558621 http://dx.doi.org/10.1242/jcs.259220 |
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