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FAM209 associates with DPY19L2, and is required for sperm acrosome biogenesis and fertility in mice

Infertility afflicts up to 15% of couples globally each year with men a contributing factor in 50% of these cases. Globozoospermia is a rare condition found in infertile men, which is characterized by defective acrosome biogenesis leading to the production of round-headed sperm. Here, we report that...

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Detalles Bibliográficos
Autores principales: Castaneda, Julio M., Shimada, Keisuke, Satouh, Yuhkoh, Yu, Zhifeng, Devlin, Darius J., Ikawa, Masahito, Matzuk, Martin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627553/
https://www.ncbi.nlm.nih.gov/pubmed/34471926
http://dx.doi.org/10.1242/jcs.259206