NF-κB determines Paneth versus goblet cell fate decision in the small intestine

Although the role of the transcription factor NF-κB in intestinal inflammation and tumor formation has been investigated extensively, a physiological function of NF-κB in sustaining intestinal epithelial homeostasis beyond inflammation has not been demonstrated. Using NF-κB reporter mice, we detecte...

Descripción completa

Detalles Bibliográficos
Autores principales: Brischetto, Cristina, Krieger, Karsten, Klotz, Christian, Krahn, Inge, Kunz, Séverine, Kolesnichenko, Marina, Mucka, Patrick, Heuberger, Julian, Scheidereit, Claus, Schmidt-Ullrich, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Stem Cells and Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627599/
https://www.ncbi.nlm.nih.gov/pubmed/34751748
http://dx.doi.org/10.1242/dev.199683

Ejemplares similares

Ejemplares similares