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GAS1 is required for NOTCH-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium

Growth arrest-specific 1 (GAS1) acts as a co-receptor to patched 1, promoting sonic hedgehog (SHH) signaling in the developing nervous system. GAS1 mutations in humans and animal models result in forebrain and craniofacial malformations, defects ascribed to a function for GAS1 in SHH signaling durin...

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Detalles Bibliográficos
Autores principales:	Marczenke, Maike, Sunaga-Franze, Daniele Yumi, Popp, Oliver, Althaus, Irene W., Sauer, Sascha, Mertins, Philipp, Christ, Annabel, Allen, Benjamin L., Willnow, Thomas E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627604/ https://www.ncbi.nlm.nih.gov/pubmed/34698766 http://dx.doi.org/10.1242/dev.200080

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