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Alveolar progenitor differentiation and lactation depends on paracrine inhibition of notch via ROBO1/CTNNB1/JAG1
In the mammary gland, how alveolar progenitor cells are recruited to fuel tissue growth with each estrus cycle and pregnancy remains poorly understood. Here, we identify a regulatory pathway that controls alveolar progenitor differentiation and lactation by governing Notch activation in mouse. Loss...
Autores principales: | Cazares, Oscar, Chatterjee, Sharmila, Lee, Pinky, Strietzel, Catherine, Bubolz, J. W., Harburg, Gwyndolen, Howard, Jon, Katzman, Sol, Sanford, Jeremy, Hinck, Lindsay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627605/ https://www.ncbi.nlm.nih.gov/pubmed/34758082 http://dx.doi.org/10.1242/dev.199940 |
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