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Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation
Microglia are integral mediators of innate immunity within the mammalian central nervous system. Typical microglial responses are transient, intending to restore homeostasis by orchestrating the removal of pathogens and debris and the regeneration of damaged neurons. However, prolonged and persisten...
Autores principales: | Chu, Erskine, Mychasiuk, Richelle, Hibbs, Margaret L., Semple, Bridgette D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627624/ https://www.ncbi.nlm.nih.gov/pubmed/34838047 http://dx.doi.org/10.1186/s12974-021-02325-6 |
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