Cargando…
Spontaneous Muscle Hematoma in Japanese Patients with Severe COVID-19 Treated with Unfractionated Heparin: Two Case Reports
In hospitalized coronavirus disease 2019 (COVID-19) patients, anticoagulation therapy is administered to prevent thrombosis. However, anticoagulation sometimes causes bleeding complications. We herein report two Japanese cases of severe COVID-19 in which spontaneous muscle hematomas (SMH) developed...
| Autores principales: | , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Japanese Society of Internal Medicine
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627824/ https://www.ncbi.nlm.nih.gov/pubmed/34433713 http://dx.doi.org/10.2169/internalmedicine.7422-21 |
| _version_ | 1784606893013991424 |
|---|---|
| author | Ito, Yu Awano, Nobuyasu Uchiyama, Fumiya Inomata, Minoru Kuse, Naoyuki Tone, Mari Takada, Kohei Fujimoto, Kazushi Muto, Yutaka Sagisaka, Shogo Maki, Kenro Yamashita, Ryuta Harada, Akinori Nishimura, Jun-ichi Hayashi, Munehiro Izumo, Takehiro |
| author_facet | Ito, Yu Awano, Nobuyasu Uchiyama, Fumiya Inomata, Minoru Kuse, Naoyuki Tone, Mari Takada, Kohei Fujimoto, Kazushi Muto, Yutaka Sagisaka, Shogo Maki, Kenro Yamashita, Ryuta Harada, Akinori Nishimura, Jun-ichi Hayashi, Munehiro Izumo, Takehiro |
| author_sort | Ito, Yu |
| collection | PubMed |
| description | In hospitalized coronavirus disease 2019 (COVID-19) patients, anticoagulation therapy is administered to prevent thrombosis. However, anticoagulation sometimes causes bleeding complications. We herein report two Japanese cases of severe COVID-19 in which spontaneous muscle hematomas (SMH) developed under therapeutic anticoagulation with unfractionated heparin. Although the activated partial prothrombin time was within the optimal range, contrast-enhanced computed tomography (CECT) revealed SMH in the bilateral iliopsoas muscles in both cases, which required emergent transcatheter embolization. Close monitoring of the coagulation system and the early diagnosis of bleeding complications through CECT are needed in severe COVID-19 patients treated with anticoagulants. |
| format | Online Article Text |
| id | pubmed-8627824 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | The Japanese Society of Internal Medicine |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-86278242021-12-10 Spontaneous Muscle Hematoma in Japanese Patients with Severe COVID-19 Treated with Unfractionated Heparin: Two Case Reports Ito, Yu Awano, Nobuyasu Uchiyama, Fumiya Inomata, Minoru Kuse, Naoyuki Tone, Mari Takada, Kohei Fujimoto, Kazushi Muto, Yutaka Sagisaka, Shogo Maki, Kenro Yamashita, Ryuta Harada, Akinori Nishimura, Jun-ichi Hayashi, Munehiro Izumo, Takehiro Intern Med Case Report In hospitalized coronavirus disease 2019 (COVID-19) patients, anticoagulation therapy is administered to prevent thrombosis. However, anticoagulation sometimes causes bleeding complications. We herein report two Japanese cases of severe COVID-19 in which spontaneous muscle hematomas (SMH) developed under therapeutic anticoagulation with unfractionated heparin. Although the activated partial prothrombin time was within the optimal range, contrast-enhanced computed tomography (CECT) revealed SMH in the bilateral iliopsoas muscles in both cases, which required emergent transcatheter embolization. Close monitoring of the coagulation system and the early diagnosis of bleeding complications through CECT are needed in severe COVID-19 patients treated with anticoagulants. The Japanese Society of Internal Medicine 2021-08-24 2021-11-01 /pmc/articles/PMC8627824/ /pubmed/34433713 http://dx.doi.org/10.2169/internalmedicine.7422-21 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Case Report Ito, Yu Awano, Nobuyasu Uchiyama, Fumiya Inomata, Minoru Kuse, Naoyuki Tone, Mari Takada, Kohei Fujimoto, Kazushi Muto, Yutaka Sagisaka, Shogo Maki, Kenro Yamashita, Ryuta Harada, Akinori Nishimura, Jun-ichi Hayashi, Munehiro Izumo, Takehiro Spontaneous Muscle Hematoma in Japanese Patients with Severe COVID-19 Treated with Unfractionated Heparin: Two Case Reports |
| title | Spontaneous Muscle Hematoma in Japanese Patients with Severe COVID-19 Treated with Unfractionated Heparin: Two Case Reports |
| title_full | Spontaneous Muscle Hematoma in Japanese Patients with Severe COVID-19 Treated with Unfractionated Heparin: Two Case Reports |
| title_fullStr | Spontaneous Muscle Hematoma in Japanese Patients with Severe COVID-19 Treated with Unfractionated Heparin: Two Case Reports |
| title_full_unstemmed | Spontaneous Muscle Hematoma in Japanese Patients with Severe COVID-19 Treated with Unfractionated Heparin: Two Case Reports |
| title_short | Spontaneous Muscle Hematoma in Japanese Patients with Severe COVID-19 Treated with Unfractionated Heparin: Two Case Reports |
| title_sort | spontaneous muscle hematoma in japanese patients with severe covid-19 treated with unfractionated heparin: two case reports |
| topic | Case Report |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627824/ https://www.ncbi.nlm.nih.gov/pubmed/34433713 http://dx.doi.org/10.2169/internalmedicine.7422-21 |
| work_keys_str_mv | AT itoyu spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports AT awanonobuyasu spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports AT uchiyamafumiya spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports AT inomataminoru spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports AT kusenaoyuki spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports AT tonemari spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports AT takadakohei spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports AT fujimotokazushi spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports AT mutoyutaka spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports AT sagisakashogo spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports AT makikenro spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports AT yamashitaryuta spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports AT haradaakinori spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports AT nishimurajunichi spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports AT hayashimunehiro spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports AT izumotakehiro spontaneousmusclehematomainjapanesepatientswithseverecovid19treatedwithunfractionatedheparintwocasereports |