Cranial Nerve Involvement and Dysautonomia in Post-COVID-19 Guillain-Barré Syndrome

The clinical characteristics of Guillain-Barré syndrome (GBS) after coronavirus disease 2019 (COVID-19) remain unclear due to the small number of cases. We herein report a case of a Japanese patient with post-COVID-19 GBS who presented with facial and limb muscle weakness, sensory deficits, and auto...

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Autores principales: Kakumoto, Toshiyuki, Kobayashi, Satoshi, Yuuki, Hayato, Kainaga, Mitsuhiro, Shirota, Yuichiro, Hamada, Masashi, Hashimoto Maeda, Meiko, Kubota, Akatsuki, Kawai, Mizuho, Saito, Masaaki, Ishiura, Hiroyuki, Toda, Tatsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627825/
https://www.ncbi.nlm.nih.gov/pubmed/34433712
http://dx.doi.org/10.2169/internalmedicine.7355-21
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author Kakumoto, Toshiyuki
Kobayashi, Satoshi
Yuuki, Hayato
Kainaga, Mitsuhiro
Shirota, Yuichiro
Hamada, Masashi
Hashimoto Maeda, Meiko
Kubota, Akatsuki
Kawai, Mizuho
Saito, Masaaki
Ishiura, Hiroyuki
Toda, Tatsushi
author_facet Kakumoto, Toshiyuki
Kobayashi, Satoshi
Yuuki, Hayato
Kainaga, Mitsuhiro
Shirota, Yuichiro
Hamada, Masashi
Hashimoto Maeda, Meiko
Kubota, Akatsuki
Kawai, Mizuho
Saito, Masaaki
Ishiura, Hiroyuki
Toda, Tatsushi
author_sort Kakumoto, Toshiyuki
collection PubMed
description The clinical characteristics of Guillain-Barré syndrome (GBS) after coronavirus disease 2019 (COVID-19) remain unclear due to the small number of cases. We herein report a case of a Japanese patient with post-COVID-19 GBS who presented with facial and limb muscle weakness, sensory deficits, and autonomic dysfunction. Nerve conduction studies revealed demyelination. Head magnetic resonance imaging showed contrast enhancement in the bilateral facial nerves. Systemic management, including intubation, intravenous immunoglobulin therapy, and rehabilitation, improved the patient's condition. This was the first Japanese case of acute inflammatory demyelinating polyneuropathy after COVID-19 and was characterized by autonomic dysfunction and facial nerve enhancement.
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spelling pubmed-86278252021-12-10 Cranial Nerve Involvement and Dysautonomia in Post-COVID-19 Guillain-Barré Syndrome Kakumoto, Toshiyuki Kobayashi, Satoshi Yuuki, Hayato Kainaga, Mitsuhiro Shirota, Yuichiro Hamada, Masashi Hashimoto Maeda, Meiko Kubota, Akatsuki Kawai, Mizuho Saito, Masaaki Ishiura, Hiroyuki Toda, Tatsushi Intern Med Case Report The clinical characteristics of Guillain-Barré syndrome (GBS) after coronavirus disease 2019 (COVID-19) remain unclear due to the small number of cases. We herein report a case of a Japanese patient with post-COVID-19 GBS who presented with facial and limb muscle weakness, sensory deficits, and autonomic dysfunction. Nerve conduction studies revealed demyelination. Head magnetic resonance imaging showed contrast enhancement in the bilateral facial nerves. Systemic management, including intubation, intravenous immunoglobulin therapy, and rehabilitation, improved the patient's condition. This was the first Japanese case of acute inflammatory demyelinating polyneuropathy after COVID-19 and was characterized by autonomic dysfunction and facial nerve enhancement. The Japanese Society of Internal Medicine 2021-08-24 2021-11-01 /pmc/articles/PMC8627825/ /pubmed/34433712 http://dx.doi.org/10.2169/internalmedicine.7355-21 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kakumoto, Toshiyuki
Kobayashi, Satoshi
Yuuki, Hayato
Kainaga, Mitsuhiro
Shirota, Yuichiro
Hamada, Masashi
Hashimoto Maeda, Meiko
Kubota, Akatsuki
Kawai, Mizuho
Saito, Masaaki
Ishiura, Hiroyuki
Toda, Tatsushi
Cranial Nerve Involvement and Dysautonomia in Post-COVID-19 Guillain-Barré Syndrome
title Cranial Nerve Involvement and Dysautonomia in Post-COVID-19 Guillain-Barré Syndrome
title_full Cranial Nerve Involvement and Dysautonomia in Post-COVID-19 Guillain-Barré Syndrome
title_fullStr Cranial Nerve Involvement and Dysautonomia in Post-COVID-19 Guillain-Barré Syndrome
title_full_unstemmed Cranial Nerve Involvement and Dysautonomia in Post-COVID-19 Guillain-Barré Syndrome
title_short Cranial Nerve Involvement and Dysautonomia in Post-COVID-19 Guillain-Barré Syndrome
title_sort cranial nerve involvement and dysautonomia in post-covid-19 guillain-barré syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627825/
https://www.ncbi.nlm.nih.gov/pubmed/34433712
http://dx.doi.org/10.2169/internalmedicine.7355-21
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