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CHD4 Conceals Aberrant CTCF-Binding Sites at TAD Interiors by Regulating Chromatin Accessibility in Mouse Embryonic Stem Cells

CCCTC-binding factor (CTCF) critically contributes to 3D chromatin organization by determining topologically associated domain (TAD) borders. Although CTCF primarily binds at TAD borders, there also exist putative CTCF-binding sites within TADs, which are spread throughout the genome by retrotranspo...

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Detalles Bibliográficos
Autores principales: Han, Sungwook, Lee, Hosuk, Lee, Andrew J., Kim, Seung-Kyoon, Jung, Inkyung, Koh, Gou Young, Kim, Tae-Kyung, Lee, Daeyoup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627837/
https://www.ncbi.nlm.nih.gov/pubmed/34764232
http://dx.doi.org/10.14348/molcells.2021.0224