A hypomorphic mutation in the mouse Csn1s1 gene generated by CRISPR/Cas9 pronuclear microinjection

Caseins are major milk proteins that have an evolutionarily conserved role in nutrition. Sequence variations in the casein genes affect milk composition in livestock species. Regulatory elements of the casein genes could be used to direct the expression of desired transgenes into the milk of transge...

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Detalles Bibliográficos
Autores principales: Smirnov, A.V., Shnaider, T.А., Korablev, A.N., Yunusova, A.M., Serova, I.A., Battulin, N.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Federal Research Center Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627868/
https://www.ncbi.nlm.nih.gov/pubmed/34901729
http://dx.doi.org/10.18699/VJ21.036

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