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Multistage hematopoietic stem cell regulation in the mouse: A combined biological and mathematical approach

We have reconciled steady-state and stress hematopoiesis in a single mathematical model based on murine in vivo experiments and with a focus on hematopoietic stem and progenitor cells. A phenylhydrazine stress was first applied to mice. A reduced cell number in each progenitor compartment was eviden...

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Detalles Bibliográficos
Autores principales: Bonnet, Céline, Gou, Panhong, Girel, Simon, Bansaye, Vincent, Lacout, Catherine, Bailly, Karine, Schlagetter, Marie-Hélène, Lauret, Evelyne, Méléard, Sylvie, Giraudier, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627979/
https://www.ncbi.nlm.nih.gov/pubmed/34877482
http://dx.doi.org/10.1016/j.isci.2021.103399