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Multistage hematopoietic stem cell regulation in the mouse: A combined biological and mathematical approach
We have reconciled steady-state and stress hematopoiesis in a single mathematical model based on murine in vivo experiments and with a focus on hematopoietic stem and progenitor cells. A phenylhydrazine stress was first applied to mice. A reduced cell number in each progenitor compartment was eviden...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627979/ https://www.ncbi.nlm.nih.gov/pubmed/34877482 http://dx.doi.org/10.1016/j.isci.2021.103399 |