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The natural sulfoglycolipid derivative SQAP improves the therapeutic efficacy of tissue factor-targeted radioimmunotherapy in the stroma-rich pancreatic cancer model BxPC-3

α-Sulfoquinovosylacyl-1,3-propanediol (SQAP) is a semi-synthetic derivative of natural sulfoglycolipid that sensitizes tumors to external-beam radiotherapy. How SQAP affects internal radiotherapy, however, is not known. Here, we investigated the effects of SQAP for radioimmunotherapy (RIT) targeting...

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Detalles Bibliográficos
Autores principales: Takakusagi, Yoichi, Sugyo, Aya, Tsuji, Atsushi B., Sudo, Hitomi, Yasunaga, Masahiro, Matsumura, Yasuhiro, Sugawara, Fumio, Sakaguchi, Kengo, Higashi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628266/
https://www.ncbi.nlm.nih.gov/pubmed/34839108
http://dx.doi.org/10.1016/j.tranon.2021.101285