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Potentially inappropriate medications at discharge among elderly patients at a single tertiary emergency medical institution in Japan: a retrospective cross‐sectional observational study

AIM: Potentially inappropriate medications (PIMs) are associated with a lower medication adherence and a higher incidence of adverse events and medical costs among elderly patients. The current study aimed to examine the prescription status of elderly patients transported to tertiary emergency medic...

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Autores principales: Aida, Kenta, Azuma, Kazunari, Mishima, Shiro, Ishii, Yuri, Suzuki, Shoji, Oda, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628299/
https://www.ncbi.nlm.nih.gov/pubmed/34876989
http://dx.doi.org/10.1002/ams2.711
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author Aida, Kenta
Azuma, Kazunari
Mishima, Shiro
Ishii, Yuri
Suzuki, Shoji
Oda, Jun
author_facet Aida, Kenta
Azuma, Kazunari
Mishima, Shiro
Ishii, Yuri
Suzuki, Shoji
Oda, Jun
author_sort Aida, Kenta
collection PubMed
description AIM: Potentially inappropriate medications (PIMs) are associated with a lower medication adherence and a higher incidence of adverse events and medical costs among elderly patients. The current study aimed to examine the prescription status of elderly patients transported to tertiary emergency medical institutions to compare the proportion of elderly patients using PIMs at admission and discharge and to investigate the characteristics of PIMs at discharge and their associated factors. METHODS: In total, 264 patients aged 75 years or older who were transferred to and discharged from the emergency room at Tokyo Medical University Hospital, a tertiary care hospital, from September 2018 to August 2019 were included in this study. We quantified the number of PIMs at admission and discharge based on the Screening Tool of Older Persons’ Potentially Inappropriate Prescriptions (STOPP) criteria version 2. The primary outcomes were the proportion of elderly patients taking at least one PIM at admission and discharge. RESULTS: The proportions of patients taking PIMs at admission and discharge were 55% (n = 175) and 28% (n = 74), respectively. Old age, greater number of PIMs at admission, and greater number of medications at discharge were directly associated with PIMs at discharge. CONCLUSIONS: Admission to tertiary care hospitals resulted in a lower number of prescribed PIMs. Elderly patients with a higher number of PIMs at admission and higher number of medications at discharge might have been prescribed with PIMs.
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spelling pubmed-86282992021-12-06 Potentially inappropriate medications at discharge among elderly patients at a single tertiary emergency medical institution in Japan: a retrospective cross‐sectional observational study Aida, Kenta Azuma, Kazunari Mishima, Shiro Ishii, Yuri Suzuki, Shoji Oda, Jun Acute Med Surg Original Articles AIM: Potentially inappropriate medications (PIMs) are associated with a lower medication adherence and a higher incidence of adverse events and medical costs among elderly patients. The current study aimed to examine the prescription status of elderly patients transported to tertiary emergency medical institutions to compare the proportion of elderly patients using PIMs at admission and discharge and to investigate the characteristics of PIMs at discharge and their associated factors. METHODS: In total, 264 patients aged 75 years or older who were transferred to and discharged from the emergency room at Tokyo Medical University Hospital, a tertiary care hospital, from September 2018 to August 2019 were included in this study. We quantified the number of PIMs at admission and discharge based on the Screening Tool of Older Persons’ Potentially Inappropriate Prescriptions (STOPP) criteria version 2. The primary outcomes were the proportion of elderly patients taking at least one PIM at admission and discharge. RESULTS: The proportions of patients taking PIMs at admission and discharge were 55% (n = 175) and 28% (n = 74), respectively. Old age, greater number of PIMs at admission, and greater number of medications at discharge were directly associated with PIMs at discharge. CONCLUSIONS: Admission to tertiary care hospitals resulted in a lower number of prescribed PIMs. Elderly patients with a higher number of PIMs at admission and higher number of medications at discharge might have been prescribed with PIMs. John Wiley and Sons Inc. 2021-11-29 /pmc/articles/PMC8628299/ /pubmed/34876989 http://dx.doi.org/10.1002/ams2.711 Text en © 2021 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Aida, Kenta
Azuma, Kazunari
Mishima, Shiro
Ishii, Yuri
Suzuki, Shoji
Oda, Jun
Potentially inappropriate medications at discharge among elderly patients at a single tertiary emergency medical institution in Japan: a retrospective cross‐sectional observational study
title Potentially inappropriate medications at discharge among elderly patients at a single tertiary emergency medical institution in Japan: a retrospective cross‐sectional observational study
title_full Potentially inappropriate medications at discharge among elderly patients at a single tertiary emergency medical institution in Japan: a retrospective cross‐sectional observational study
title_fullStr Potentially inappropriate medications at discharge among elderly patients at a single tertiary emergency medical institution in Japan: a retrospective cross‐sectional observational study
title_full_unstemmed Potentially inappropriate medications at discharge among elderly patients at a single tertiary emergency medical institution in Japan: a retrospective cross‐sectional observational study
title_short Potentially inappropriate medications at discharge among elderly patients at a single tertiary emergency medical institution in Japan: a retrospective cross‐sectional observational study
title_sort potentially inappropriate medications at discharge among elderly patients at a single tertiary emergency medical institution in japan: a retrospective cross‐sectional observational study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628299/
https://www.ncbi.nlm.nih.gov/pubmed/34876989
http://dx.doi.org/10.1002/ams2.711
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